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Mirko Koppen Selected Research

m-AAA proteases

10/2009Autocatalytic processing of m-AAA protease subunits in mitochondria.
1/2007Variable and tissue-specific subunit composition of mitochondrial m-AAA protease complexes linked to hereditary spastic paraplegia.
10/2005The m-AAA protease defective in hereditary spastic paraplegia controls ribosome assembly in mitochondria.
11/2003Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia.

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Mirko Koppen Research Topics

Disease

3Hereditary Spastic Paraplegia
01/2007 - 11/2003
2Mitochondrial Diseases (Mitochondrial Disease)
03/2013 - 10/2005
1Neurodegenerative Diseases (Neurodegenerative Disease)
10/2009

Drug/Important Bio-Agent (IBA)

4m-AAA proteasesIBA
10/2009 - 11/2003
1Proteins (Proteins, Gene)FDA Link
03/2013
1RNA (Ribonucleic Acid)IBA
03/2013
1ATPases Associated with Diverse Cellular ActivitiesIBA
10/2005
1Metalloproteases (Metalloproteinases)IBA
11/2003